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cd45rb high cells  (Jackson Laboratory)

 
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    Jackson Laboratory cd45rb high cells
    Cd45rb High Cells, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cd45rb high cells/product/Jackson Laboratory
    Average 90 stars, based on 1 article reviews
    cd45rb high cells - by Bioz Stars, 2026-03
    90/100 stars

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    cd45rb high cells  (Jackson Laboratory)
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    Cd45rb High Cells, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    cd4 + cd45rb high naïve t cells  (Becton Dickinson)
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    ( A ) Histology of the colonic lamina propria demonstrates significant villus distortion in WT <t>CD45RB</t> High T cell recipients relative to miR-106a −/− T cell recipients following adoptive transfer ( B ) Adoptive transfer of <t>CD4</t> + CD45RB High T cells from miR-106a −/− mice resulted in significantly attenuated weight loss, a surrogate marker of intestinal inflammation, relative to WT controls. This result coincided with a significant reduction in IFN + CD4 + T cells ( C ) and IL-17 + CD4 + T cells ( D ) in the colonic lamina propria as well as a reduction in IL-10-producing CD4 + T cells ( E ). Results represent mean ± SEM for 4–7 mice per group from two or more independent studies. *P<0.05, **P<0.01, ***P<0.001.
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    ( A ) Histology of the colonic lamina propria demonstrates significant villus distortion in WT CD45RB High T cell recipients relative to miR-106a −/− T cell recipients following adoptive transfer ( B ) Adoptive transfer of CD4 + CD45RB High T cells from miR-106a −/− mice resulted in significantly attenuated weight loss, a surrogate marker of intestinal inflammation, relative to WT controls. This result coincided with a significant reduction in IFN + CD4 + T cells ( C ) and IL-17 + CD4 + T cells ( D ) in the colonic lamina propria as well as a reduction in IL-10-producing CD4 + T cells ( E ). Results represent mean ± SEM for 4–7 mice per group from two or more independent studies. *P<0.05, **P<0.01, ***P<0.001.

    Journal: Mucosal immunology

    Article Title: miR-106a deficiency attenuates inflammation in murine IBD models.

    doi: 10.1038/s41385-018-0091-7

    Figure Lengend Snippet: ( A ) Histology of the colonic lamina propria demonstrates significant villus distortion in WT CD45RB High T cell recipients relative to miR-106a −/− T cell recipients following adoptive transfer ( B ) Adoptive transfer of CD4 + CD45RB High T cells from miR-106a −/− mice resulted in significantly attenuated weight loss, a surrogate marker of intestinal inflammation, relative to WT controls. This result coincided with a significant reduction in IFN + CD4 + T cells ( C ) and IL-17 + CD4 + T cells ( D ) in the colonic lamina propria as well as a reduction in IL-10-producing CD4 + T cells ( E ). Results represent mean ± SEM for 4–7 mice per group from two or more independent studies. *P<0.05, **P<0.01, ***P<0.001.

    Article Snippet: Adoptive transfer colitis was induced by intraperitoneal injection of 1×10 6 cells/mouse of magnetically pre-enriched CD4 + T cells (EasySEP, STEMCELL Technologies, Vancouver, Ca) flow sorted into live CD4 + CD45RB High naïve T cells (BD FACSAria II, BD Biosciences, Franklin Lakes, NJ).

    Techniques: Adoptive Transfer Assay, Marker